Fri Feb 06 2026

41 articles - From Friday Jan 30 2026 to Friday Feb 06 2026

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Hepatology
Impact of newer antihyperglycemic agents on hepatic complications: A systematic review and meta-analysis of data from 5.3 million patients with type 2 diabetes mellitus.

GLP-1 RAs and SGLT-2 inhibitors were associated with hepatoprotective effects compared with other glucose-lowering therapies in patients with T2DM, with GLP-1 RAs showing additional benefits in chronic liver disease. These findings provide evidence on the relationships between antidiabetic drug classes and liver-related outcomes in patients with T2DM and may inform clinical decision-making.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Clin Gastroenterol Hepatol
Diagnostic Accuracy of Non-Invasive Tests for MASLD Across Age, Type 2 Diabetes, and Obesity Subgroups: A Multinational Study.

Accuracy of non-invasive tests for advanced fibrosis in MASLD is influenced by age, T2D, and obesity. Age-adjusted FIB-4 thresholds may enhance risk stratification. Imaging-based and composite NITs (LSM and Agile-3+) provide more consistent performance across MASLD subpopulations.

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Gaze shift to screen edge boosts colorectal adenoma detection: multicenter randomized controlled trial (EYE-SIGHT trial).

Increased peripheral gaze by real-time guidance significantly improved adenoma and polyp detection without extending procedure time. This low-burden, scalable approach may offer a simple, effective method to improve colonoscopy. UMIN-CTR, UMIN000055006,

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Peppermint oil and sweets in pediatric irritable bowel syndrome and functional abdominal pain: a randomized trial.

Neither peppermint oil nor peppermint sweets were superior to placebo in treating paediatric IBS and FAP-NOS. These findings suggest prioritizing proven gut-brain axis-targeted interventions for this population.

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Tailored treatment of functional dyspepsia with nortriptyline: a multi-center, double-blind, placebo-controlled trial.

Nortriptyline was not more effective than placebo in reducing FD symptoms in participants pre-selected based on CYP2D6 genotype, although a biological effect of nortriptyline could not be ruled out. However, effects related to participants' belief appeared to be stronger; number, NCT03652571.

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Ustekinumab and JAK inhibitors outperform vedolizumab as second-line therapy in anti-TNF-experienced patients with ulcerative colitis.

Ustekinumab and JAKi were more effective than vedolizumab in inducing steroid-free and biochemical remission following anti-TNFα failure. Safety concerns with JAKi warrant careful patient selection in clinical practice.

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Gut
Effect of long-term adherence on faecal immunochemical test positivity rate, positive predictive value and detection rate in organised population-based colorectal cancer screening.

After an initial round with the highest FIT-positivity and detection rates, screening outcomes stabilise at lower levels reflecting neoplasia removal and subsequent selection of a lower-risk population. Because detection rates remain clinically relevant even in an adherent cohort, early screening cessation after a sequence of normal biennial FITs is not justified.

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Integrative proteogenomics maps multifactorial aetiology, progression and therapeutic vulnerabilities in gastric cancer.

This proteogenomic framework defines exposure-informed and microbiome-informed gastric cancer subtypes, providing a molecular schema for patient stratification, prevention and actionable therapeutic vulnerabilities.

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Post-infection disorders of gut-brain interaction: results of the Rome Foundation Global Epidemiology Study.

PI-DGBI represents a significant subset of DGBI, with distinct sociodemographic and clinical characteristics. These findings highlight the role of acute gastroenteritis in triggering the onset of long-term gastrointestinal disorders and underscore the need for targeted interventions to mitigate its impact on patient health.

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Prospective evaluation of radical surgery for adenocarcinoma of oesophagogastric junction: real-world insights from the CLAEG study.

The CLAEG study shows that abdominal lymphadenectomy should be prioritised in AEG, with neoadjuvant therapy, total gastrectomy and laparoscopy associated with favourable short-term outcomes.

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Hepatology
Incorporating artificial intelligence into imaging for surveillance and diagnosis of liver cancer: Innovations, challenges, and clinical translation.

Large, prospective multicenter validation studies are essential to confirm clinical benefit and safety. Ultimately, the careful implementation of trustworthy and explainable AI tools could enable earlier detection, greater diagnostic precision, and more equitable liver cancer care.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link


Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Gastroenterol
2026 CME Information.

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Calendar of Courses, Symposiums and Conferences.

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Letter to the Editor.

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Response to Chinitz and Menon.

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Clin Gastroenterol Hepatol
Periampullary Subepithelial Pseudotumor in Acute Cholangitis.

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Endoscopy
A case involving a submucosal bulge in the duodenal bulb was ultimately confirmed to be a residual gallbladder.

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A novel 6 Fr inside biliary stent system for perihilar biliary drainage.

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A novel endoscopic ultrasound system assisted by artificial intelligence for the recognition of pancreatic parenchyma and the detection of solid/cystic lesions.

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A triple-guidewire technique to stabilize the endoscope during endoscopic ultrasonography-guided pancreatic drainage following pancreaticoduodenectomy.

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Arterial bleeding during endoscopic ultrasound-guided pancreatic pseudocyst drainage using a novel ultrasound processor.

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Combined gastric mucosal ablation of the fundus using a new hybrid device with endoscopic sleeve gastroplasty for obesity.

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Diagnosis of gallbladder villous tubular adenoma with high-grade intraepithelial neoplasia via peroral endoscopic choledochoscopy: a rare case of an elderly patient.

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Endoscopic closure of a gastrocutaneous fistula reopening 18 years after gastrostomy removal using argon plasma coagulation and endoscopic hand suturing.

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Endoscopic removal of esophageal bezoars using a condom as a novel retrieval device.

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Endoscopic rescue after lumen-apposing metal stent deployment failure during endoscopic ultrasound-guided drainage of a giant pancreatic pseudocyst.

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Endoscopic ultrasonography-guided B3 branch drainage/anastomosis as hepaticoduodenostomy in atrophic left hepatic lobe case.

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Endoscopic ultrasound-guided perforator-targeted embolization for gastric variceal bleeding due to left-sided portal hypertension.

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Fluoroscopy-guided, sheath-assisted biopsy for indeterminate intraductal biliary masses.

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Gel immersion electrohydraulic lithotripsy for gallbladder stones through a lumen-apposing metal stent.

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Novel application of metal-clip traction-assisted endoscopic intermuscular dissection for a rare calcifying fibrous tumor.

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Peroral cholangiopancreatoscopy-guided diagnosis and treatment of an intramural bile duct stone complicated with immunoglobulin G4-related cholangitis: a case report with video.

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Side-by-side placement and removability of a novel multi-hole self-expandable metallic stent for malignant hilar biliary obstruction.

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Use of a Zenker's diverticulum overtube for the safe extraction of an unusual gastric foreign body.

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Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther
Letter: Rifaximin Versus Low FODMAP Diet in IBS: What the Primary Endpoint Does Not Tell Us.

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Letter: Rifaximin Versus Low FODMAP Diet in IBS: What the Primary Endpoint Does Not Tell Us. Authors' Reply.

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Gastroenterology
Comments on "Total Pancreatectomy With Islet Autotransplantation for Chronic Pancreatitis".

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Diet and Chronic Constipation: Key Considerations of Subtype Specificity, Synergistic Effects, and Temporal Dynamics.

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Gut
Challenges in defining MASLD in lean individuals: the impact of the Fatty Liver Index on phenotypic characterisation.

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Clarifying the decision rules and implementation boundaries for risk-based HCC surveillance in MASLD.

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Real-world treatment patterns in microscopic colitis: a nationwide study from Sweden.

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